TY - DATA T1 - Data underlying the publication: Co-translational ribosome pairing enables native assembly of misfolding-prone subunits PY - 2025/06/17 AU - Katharina Till AU - Florian Wruck AU - Jaro Schmitt AU - Kai Fenzl AU - Matilde Bertolini AU - Frank Tippmann AU - Alexandros Katranidis AU - Bernd Bukau AU - Günter Kramer AU - Sander J. Tans UR - DO - 10.4121/d7af49d7-3ece-4b65-8007-11cc07650137.v1 KW - optical tweezer KW - single-molecule KW - protein folding KW - protein assembly KW - disome selective profiling N2 -
This dataset contains data collected during correlated single-molecule force spectroscopy and multi-color confocal laser scanning spectroscopy experiments at AMOLF, as part of Katharina Till's PhD Thesis project. The objective of the project behind this data was to use disome selective ribosome profiling (DiSP) to detect co-translational assembly of the intermediate filament lamin in vivo and optical tweezers are to study folding and assembly transitions for individual monomers and dimers in vitro. The data included in this data set has been organised per figure of the corresponding to be published publication. The excel sheet contains several tabs containing the underlying data to the figures they are named after. The data is being made public both to act as supplementary data for publications and the PhD thesis of Katharina Till and in order for other researchers to use this data in their own work.
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