Data underlying the publication: "Lateral induction limits the impact of cell connectivity on Notch signaling in arterial walls"

DOI:10.4121/12854297.v1
The DOI displayed above is for this specific version of this dataset, which is currently the latest. Newer versions may be published in the future. For a link that will always point to the latest version, please use
DOI: 10.4121/12854297

Datacite citation style

Tommaso Ristori; Stassen, O. M. J. A. (Oscar); Sahlgren, C. M. (Cecilia); Loerakker, S. (Sandra) (2020): Data underlying the publication: "Lateral induction limits the impact of cell connectivity on Notch signaling in arterial walls". Version 1. 4TU.ResearchData. dataset. https://doi.org/10.4121/12854297.v1
Other citation styles (APA, Harvard, MLA, Vancouver, Chicago, IEEE) available at Datacite

Dataset

Usage statistics

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Time coverage

2020

Licence

CC BY 4.0

Interoperability

This study extends a previous 1D agent-based model for Notch signaling in arteries to a 2D formulation. This allows investigation of the effects of cell connectivity on the dynamics of arterial Notch signaling and VSMC phenotypes. Notch signaling for VSMCs with 2-6 neighbouring cells was analyzed. Computational results of the 1D and 2D formulations were also compared.

History

  • 2020-10-20 first online, published, posted

Publisher

4TU.ResearchData

Funding

  • The integration of cell signalling and mechanical forces in vascular morphology (grant code 771168) [more info...] European Research Council
  • Predicting cardiovascular regeneration: integrating mechanical cues and signaling pathways (grant code 802967) [more info...] European Research Council
  • Targeting Notch signalign in cancer (grant code 218062) [more info...] Academy of Finland

Organizations

Eindhoven University of Technology, Department of Biomedical Engineering;
Åbo Akademi University, Faculty of Science and Engineering, Biosciences;
Eindhoven University of Technology, Institute for Complex Molecular Systems

DATA

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